Category: Psilocybe
Potency Level: Medium — balanced effects with moderate psilocybin content, ideal for beginners and experienced users alike.
Edibility: Hallucinogenic edible

What is F+? A Complete Overview

F+ is a notable strain of the species Psilocybe cubensis, widely recognized among mushroom enthusiasts and cultivators for its balanced effects and adaptability. It is not derived from a wild specimen but rather selectively developed from domesticated lines, making it easy to cultivate under consistent conditions. The origins of its name are somewhat mysterious, with theories ranging from its creator's initial to sensory descriptions of its effects.

Morphologically, F+ features medium-to-large mushrooms with dense fruiting bodies. They have caramel-colored convex caps that can fade to a tan hue as they mature, paired with sturdy and fleshy white stalks. As with other Psilocybe cubensis strains, the gills underneath the cap start out light but darken as spores develop.

F+ is often appreciated by cultivators for being a prolific fruiter that isn't overly demanding, producing generous flushes even under basic or minimal setups. Its hallucinogenic effects tend to be balanced — not overly intense, making it a popular entry point for beginners interested in experiencing psilocybin mushrooms. Its psychoactive profile typically includes mild visual distortions, slight time dilation, moderate euphoria, and introspective reflection.

While it may not be as potent as strains like Penis Envy or Albino A+, its consistency and resilience in cultivation have made F+ a longstanding presence within home grower circles and the broader psychedelic mushroom community.

Taxonomic Classification

Kingdom:Fungi
Division:Basidiomycota
Class:Agaricomycetes
Order:Agaricales
Family:Hymenogastraceae
Genus:Psilocybe
Species:cubensis
Type:Classic
Cross:None

Origin and Traditional Use of F+

The F+ strain of Psilocybe cubensis does not have Indigenous or traditional historical roots, as it was developed through modern mushroom cultivation efforts. Unlike ancient strains found in regions like Mesoamerica — utilized in ritualistic ceremonies by the Mazatec, Mixtec, or Zapotec peoples — F+ carries a more recent provenance that aligns with the resurgence of psychedelic research and personal growth exploration.

Emerging in the mycology circles of North America, F+ has primarily gained popularity thanks to online forums, underground spore trading communities, and DIY cultivation movements. Its proliferation came about during the 1990s and early 2000s as home cultivation became increasingly popular, coinciding with a cultural shift towards alternative healing, personal development, and psychonautical exploration.

There are no sacred rites or legends tied specifically to F+ as with more ancestrally found mushrooms such as Psilocybe mexicana or Psilocybe zapotecorum. Nevertheless, it plays a key role in pseudo-modern psychedelic culture: a user-friendly strain that embodies the spirit of accessibility and curiosity. F+ contributes to democratizing the mycological experience, allowing self-explorers and hobbyist growers to connect with the entheogenic experience in the absence of formal initiation.

This strain represents the cultural transition of psychedelic mushrooms from Indigenous sacramental use to present-day Western individualistic experimentation. It offers a gateway experience shaped by Internet knowledge transfers, amateur cultivation guides, and the broader movement toward cognitive liberty and conscious self-discovery.

How to Cultivate F+

Difficulty Level: Beginner - ideal entry point for novice growers due to its adaptability, resilience, and high-yielding properties.

Substrate Requirements:

  • Pre-sterilized milo grain bags for colonization
  • CVG (Coco Coir, Vermiculite, Gypsum) substrate for fruiting
  • All-in-One Grow Kits available for simple cultivation
  • Manure-based substrates (traditional option)

Environmental Conditions:

  • Colonization Temperature: 75°F to 81°F (24°C–27°C)
  • Fruiting Temperature: 72°F (22°C)
  • Humidity: 85%–95% during fruiting
  • Air Exchange: Fresh Air Exchange (FAE) crucial for cap development
  • Lighting: Indirect or diffused light helps trigger pinning

Timeline:

  • Colonization: 10–14 days typical under proper conditions
  • Fruiting: 2–3 major flushes expected
  • Yield: Moderate to large mushrooms with generous flushes

Cultivation Notes: F+ thrives on various substrates but performs exceptionally well with CVG, which eliminates the inconsistent microbial profile of manure while offering optimal water retention and aeration. The strain is forgiving to beginners and rewards consistent care with beautiful fruiting bodies and stable potency cycles. Clean techniques, proper substrate layers, and sterilized tools are key to successful cultivation.

Where Do F+ Mushrooms Typically Grow?

F+ is a domesticated variety of Psilocybe cubensis and isn't typically found in the wild. Like other cubensis strains, its natural relatives do occur in tropical and subtropical climates, often in nutrient-rich fields where bovine livestock is present. These include agricultural grasslands, humid tropical forests, and disturbed pastures with rich soil content.

Naturally occurring cubensis mushrooms tend to thrive in regions such as Central America, Southeast Asia, the Gulf Coast of the United States, South America's northern territories, India's Eastern Ghats, and parts of Australia. They are often spotted during the rainy seasons when the environment meets critical moisture levels that support fungal propagation.

Key environmental conditions for wild cubensis include:

  • High humidity (above 80%)
  • Consistent warmth ranging between 75°F–85°F (24°C–29°C)
  • Semi-open spaces where oxygen flow supports mature cap formation
  • Nutrient-rich soils from manure-enriched environments
  • Decomposing plant matter in low-altitude tropical forests

For cultivated F+, these conditions are mimicked through controlled indoor settings. While genetically similar to wild cubensis mushrooms, F+ has been selectively adapted over many generations for optimal indoor fruiting. As such, it is rarely (if ever) found growing in outdoor environments naturally, particularly in temperate zones where the climate isn't conducive to survival without human intervention.

When are F+ Mushrooms in Season?

Late spring through early autumn in the wild; year-round indoors under controlled cultivation conditions.

Are F+ Mushrooms Edible or Toxic?

Status: Hallucinogenic edible

Toxicity Information:

Psilocybe cubensis strains, including F+, are not considered toxic when consumed in appropriate doses. However, they are classified as hallucinogenic and can produce intense psychoactive effects that may be psychologically distressing or destabilizing in certain individuals.

Physical Risks:
  • Overconsumption can result in excessive cognitive and sensory disruptions
  • Potential for anxiety, paranoia, derealization, and overwhelmingly intense hallucinations
  • Temporary psychosis-like symptoms, confusion, or loss of motor coordination at high doses
  • Nausea, vomiting, or muscle tension may occur during onset and peak phases
Risk Factors:

Individuals predisposed to mental health conditions such as bipolar disorder or schizophrenia may experience aggravated symptoms. Toxicological risks emerge primarily from misidentification with dangerous lookalikes or consumption in unsupervised or stressful environments.

F+ itself does not contain amatoxins or muscarine and is not lethal. However, co-ingestion with alcohol, MAO inhibitors, or multiple psychoactive compounds can elevate physiological burden and psychological danger. Trip sitters or guides are highly recommended for inexperienced users.

What are the Medicinal Uses for F+?

While F+ is primarily known for its psychoactive effects rather than as a therapeutic medicine, emerging research into psilocybin — the primary alkaloid found in Psilocybe cubensis — reveals promising medicinal and psychological benefits. F+, as a medium-potency strain, can deliver psilocybin content sufficient for numerous therapeutic applications, notably in microdosing or controlled psychedelic therapy under supervision.

Potential Benefits:

  • Mental Health Applications: Clinical studies show psilocybin helps reduce symptoms of treatment-resistant depression, PTSD, OCD, and anxiety, especially related to end-of-life distress
  • Neuroplasticity Enhancement: Psilocybin interacts with serotonin receptors, particularly 5-HT2A, eliciting neuroplastic benefits and emotional recalibration
  • Cluster Headache Management: Anecdotal reports suggest extended remission of pain cycles
  • Microdosing Applications: May support enhanced creativity, increased focus, emotional regulation, and decreased anxiety

F+'s balanced alkaloid profile may make it more suited than highly potent strains for medicinal users, allowing a controlled ascent without overwhelming visuals. For individuals aiming to use psychedelics for intention-based healing, journaling, or guided trips with a therapeutic aim, F+ can serve as a reliable ally.

Important: Medicinal use should always be done in legal, supervised settings to mitigate risks and ensure safe outcomes. Scientific validation of many therapeutic benefits remains ongoing.

What Drugs Interact with F+?

Interactions with Prescription Medications:

  • MAO Inhibitors (MAOIs): Natural (Syrian rue) or pharmaceutical (phenelzine) MAOIs can potentiate psilocybin effects to potentially dangerous levels, extending trip duration and intensifying effects
  • SSRI/SNRI Antidepressants: Medications like fluoxetine, sertraline, or venlafaxine can dampen the effects of F+ by blocking serotonin receptors
  • Antipsychotic Medications: Direct conflicts in neural receptor activity can lead to unpredictable or blunted effects

Other Substances:

  • Stimulants: Adderall or cocaine pose risks of cardiovascular strain
  • Alcohol & Benzodiazepines: Can dull the psychedelic or increase confusion and impulse loss
  • Cannabis: Common pairing that can manage nausea or intensify visuals, but may heighten anxiety or shift the trip into overwhelming territory
  • Herbal Supplements: St. John's Wort or kava warrant caution due to central nervous system modulation

Important: A clean, substance-free baseline is the safest practice for experiencing the full profile of F+ safely and authentically. Users on any medications should consult healthcare providers before use.

What Mushrooms Look Like F+?

F+ is a cultivated strain of Psilocybe cubensis, and when grown indoors under controlled conditions, there is little risk of confusion. However, when encountered in the wild or bought from unreliable sources, some species may resemble F+ and pose serious health risks:

  • Galerina marginata (Deadly Galerina): Shares similar cap color and general mushroom shape but contains fatally toxic amatoxins. Key distinction: Galerina grows on decaying wood, while cubensis grows from dung-enriched soil
  • Conocybe filaris: Small rust-colored mushroom containing deadly amatoxins, may be mistaken for young Psilocybe despite more slender shape
  • Pholiotina rugosa: May mimic caramel caps of cubensis but lacks blue bruising — a critical trait of psilocybin-containing species
  • Hypholoma species: Similar coloration but do not exhibit blue oxidation when handled
  • Other Psilocybe cubensis strains: B+, Ecuadorian, or Golden Teacher may be confused with F+ but are generally safe (though varying in potency)

Safety Note: Blue bruising when handled is a critical identification feature of psilocybin mushrooms. Correct identification is imperative — cultivators should source spores from reputable suppliers and avoid wild foraging unless accompanied by a mycology expert.

Disclaimer: This information is for educational, taxonomy, and research purposes only. Always consult a trained professional before attempting to identify any mushroom. Always consult a trained healthcare professional before attempting to ingest any mushroom. Do not message asking if we sell cultures or spores, all requests will be ignored. Always respect your local laws.

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